Effect of Transmural Differences in Excitation-Contraction Delay and Contraction Velocity on Left Ventricle Isovolumic Contraction: A Simulation Study
نویسندگان
چکیده
منابع مشابه
Transmural myocardial mechanics during isovolumic contraction.
OBJECTIVES We sought to resolve the 3-dimensional transmural heterogeneity in myocardial mechanics observed during the isovolumic contraction (IC) phase. BACKGROUND Although myocardial deformation during IC is expected to be little, recent tissue Doppler imaging studies suggest dynamic myocardial motions during this phase with biphasic longitudinal tissue velocities in left ventricular (LV) l...
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The echographic isovolumic contraction time (ICT) of the left ventricle (LV) was measured in order to assess alterations of LV performance in children with various forms of cardiac disease. The echographic ICT was defined as the interval between coaptation of the anterior and posterior mitral valve leaflets and aortic cusp opening. Four groups of patients were evaluated: normal (48); LV myocard...
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The effects of changes in action potential waveform on excitation–contraction coupling in mammalian ventricle were first identified almost 40 years ago.1 Many important details concerning the relationship between action potential duration and tension development have been elucidated.2 Recent work has demonstrated significant effects on the intracellular Ca transient and excitation–contraction c...
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Heart Failure After Myocardial Infarction : Altered Excitation-Contraction Coupling Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2001 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/hc3201.092285 2001;104:688-693 Circulation. http://circ.ahajournals.org/content/10...
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Previous studies have demonstrated that the ability of (.adrenergic receptor (.BAR) stimulation to increase cardiac contractility declines with aging. In the present study, the control mechanisms of excitation-contraction (EC) coupling, including calcium current (Ice), cytosolic Ca2" (Ca?') transient and contraction in response to BAR stimulation were investigated in ventricular myocytes isolat...
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ژورنال
عنوان ژورنال: BioMed Research International
سال: 2018
ISSN: 2314-6133,2314-6141
DOI: 10.1155/2018/4798512